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IL1R1
Loading...Anti-IL1R1 ProductsBackground
Anti-IL1R1 Products
- Hamster Anti-Il1r1 Recombinant Antibody (clone JAMA147) (NEUT-1293CQ)
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- Species Reactivity: Mouse
- Type: Hamster IgG
- Application: Neut
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- Rat Anti-Il1r1 Recombinant Antibody (clone CBL936) (NEUT-1294CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: ELISA, IP, Neut, WB
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- Rat Anti-Il1r1 Recombinant Antibody (clone CBL937) (NEUT-1295CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: Neut, WB
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013]
Protein class
Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Transporters
Predicted location
Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Glandular and luminal cells, Endometrial stromal cells, Langerhans cells, Hepatic stellate cells, Endometrial ciliated cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (ASC diff, ASC TERT1, HHSteC, HSkMC)
Interaction
The interleukin-1 receptor complex is a heterodimer of IL1R1 and IL1RAP. Interacts with PIK3R1.
Molecular function
Hydrolase, Receptor
More Types Infomation
Related Diseases
Maturity Onset Diabetes of the Young