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INSRR
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Protein class
Enzymes, Metabolic proteins
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Spermatogonia, Spermatocytes, Early spermatids, Cardiomyocytes, Bipolar cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (SCLC-21H, SH-SY5Y)
Interaction
Probable tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain.
Molecular function
Kinase, Receptor, Transferase, Tyrosine-protein kinase
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P
- Rabbit Anti-INSRR Recombinant Antibody (clone JM22-38) (MRO-0846-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, FC
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For Research Use Only. Not For Clinical Use.