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IRX2

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For Research Use Only. Not For Clinical Use.


IRX2 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.[supplied by OMIM, Apr 2004]
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Group enriched (Basal keratinocytes, Breast myoepithelial cells, Breast glandular cells, Suprabasal keratinocytes, Alveolar cells type 1, Alveolar cells type 2)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, BEWO, HaCaT, hTCEpi, SK-BR-3)

Molecular function

DNA-binding

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