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Integrin αvβ6

Anti-Integrin αvβ6 Products

Human Anti-Integrin αvβ6 Recombinant Antibody (TAB-449CL) (TAB-449CL)
- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib, FuncS
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Anti-human Integrin αvβ6 Recombinant Antibody (TAB-760LC) (TAB-760LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
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Anti-human Integrin αvβ6 Fab Fragment (TAB-761LC-F(E)) (TAB-761LC-F(E))
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-human Integrin αvβ6 Fab Fragment (TAB-763LC-F(E)) (TAB-763LC-F(E))
- Species Reactivity: Macaque
- Type: Human antibody
- Application: ELISA
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Anti-human Integrin αvβ6 Fab Fragment (TAB-764LC-F(E)) (TAB-764LC-F(E))
- Species Reactivity: Macaque
- Type: Human antibody
- Application: ELISA
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Anti-human Integrin αvβ6 Fab Fragment (TAB-765LC-F(E)) (TAB-765LC-F(E))
- Species Reactivity: Macaque
- Type: Human antibody
- Application: ELISA
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Afuco™ Anti-Human Integrin αvβ6 ADCC Recombinant Antibody (264RAD), ADCC Enhanced (AFC-431CL)
- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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Anti-human Integrin αvβ6 scFv Fragment (TAB-759LC-S(P)) (TAB-759LC-S(P))
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-human Integrin αvβ6 scFv Fragment (TAB-760LC-S(P)) (TAB-760LC-S(P))
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-human Integrin αvβ6 scFv Fragment (TAB-761LC-S(P)) (TAB-761LC-S(P))
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-human Integrin αvβ6 scFv Fragment (TAB-763LC-S(P)) (TAB-763LC-S(P))
- Species Reactivity: Macaque
- Type: Human antibody
- Application: ELISA
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Anti-human Integrin αvβ6 scFv Fragment (TAB-764LC-S(P)) (TAB-764LC-S(P))
- Species Reactivity: Macaque
- Type: Human antibody
- Application: ELISA
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Anti-human Integrin αvβ6 Recombinant Antibody (TAB-761LC) (TAB-761LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
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Anti-human Integrin αvβ6 Recombinant Antibody (TAB-763LC) (TAB-763LC)
- Species Reactivity: Macaque
- Type: Human antibody
- Application: Cyt, FuncS, Inhib
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Anti-human Integrin αvβ6 Recombinant Antibody (TAB-764LC) (TAB-764LC)
- Species Reactivity: Macaque
- Type: Human antibody
- Application: Cyt, FuncS, Inhib
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Anti-human Integrin αvβ6 Recombinant Antibody (TAB-765LC) (TAB-765LC)
- Species Reactivity: Macaque
- Type: Human antibody
- Application: Cyt, FuncS, Inhib
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Human Anti-αvβ6 Recombinant Antibody (HPAB-AP489-YC) (HPAB-AP489-YC)
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human, Cynomolgus, Mouse
- Type: Humanized IgG
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody (HPAB-AP490-YC) (HPAB-AP490-YC)
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody (HPAB-AP491-YC) (HPAB-AP491-YC)
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody (HPAB-AP492-YC) (HPAB-AP492-YC)
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody (HPAB-AP493-YC) (HPAB-AP493-YC)
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody (HPAB-AP494-YC) (HPAB-AP494-YC)
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human, Cynomolgus, Mouse, Rat
- Type: Humanized IgG
- Application: ELISA, FC, FuncS
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Anti-human Integrin αvβ6 scFv Fragment (TAB-765LC-S(P)) (TAB-765LC-S(P))
- Species Reactivity: Macaque
- Type: Human antibody
- Application: ELISA
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Human Anti-αvβ6 Recombinant Antibody (HPAB-AP495-YC) (HPAB-AP495-YC)
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC, FuncS
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Anti-human Integrin αvβ6 Fab Fragment (TAB-759LC-F(E)) (TAB-759LC-F(E))
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
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Anti-human Integrin αvβ6 Fab Fragment (TAB-760LC-F(E)) (TAB-760LC-F(E))
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
Compare

Anti-human Integrin αvβ6 Recombinant Antibody (TAB-759LC) (TAB-759LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
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Anti-human Integrin αvβ6 scFv Fragment (TAB-758LC-S(P)) (TAB-758LC-S(P))
- Application: ELISA, FC
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Human Anti-αvβ6 Recombinant Antibody; scFv Fragment (HPAB-AP489-YC-S(P)) (HPAB-AP489-YC-S(P))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human, Cynomolgus, Mouse
- Type: Humanized scFv
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody; scFv Fragment (HPAB-AP490-YC-S(P)) (HPAB-AP490-YC-S(P))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody; scFv Fragment (HPAB-AP491-YC-S(P)) (HPAB-AP491-YC-S(P))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody; scFv Fragment (HPAB-AP492-YC-S(P)) (HPAB-AP492-YC-S(P))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody; scFv Fragment (HPAB-AP493-YC-S(P)) (HPAB-AP493-YC-S(P))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC, FuncS
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Anti-human Integrin αvβ6 Fab Fragment (CSβ6) (TAB-756LC-F(E))
- Application: ELISA
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Anti-human Integrin αvβ6 Fab Fragment (10D5) (TAB-757LC-F(E))
- Application: ELISA
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Anti-human Integrin αvβ6 Fab Fragment (TAB-758LC-F(E)) (TAB-758LC-F(E))
- Application: ELISA, FC
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Human Anti-αvβ6 Recombinant Antibody; Fab Fragment (HPAB-AP493-YC-F(E)) (HPAB-AP493-YC-F(E))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, FuncS
Compare

Human Anti-αvβ6 Recombinant Antibody; Fab Fragment (HPAB-AP494-YC-F(E)) (HPAB-AP494-YC-F(E))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human, Cynomolgus, Mouse, Rat
- Type: Humanized Fab
- Application: ELISA, FC, FuncS
Compare

Human Anti-αvβ6 Recombinant Antibody; Fab Fragment (HPAB-AP495-YC-F(E)) (HPAB-AP495-YC-F(E))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, FuncS
Compare

Human Anti-αvβ6 Recombinant Antibody; scFv Fragment (HPAB-AP494-YC-S(P)) (HPAB-AP494-YC-S(P))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human, Cynomolgus, Mouse, Rat
- Type: Humanized scFv
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody; scFv Fragment (HPAB-AP495-YC-S(P)) (HPAB-AP495-YC-S(P))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC, FuncS
Compare

Human Anti-αvβ6 Recombinant Antibody; Fab Fragment (HPAB-AP489-YC-F(E)) (HPAB-AP489-YC-F(E))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human, Cynomolgus, Mouse
- Type: Humanized Fab
- Application: ELISA, FC, FuncS
Compare

Human Anti-αvβ6 Recombinant Antibody; Fab Fragment (HPAB-AP490-YC-F(E)) (HPAB-AP490-YC-F(E))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, FuncS
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Human Anti-αvβ6 Recombinant Antibody; Fab Fragment (HPAB-AP491-YC-F(E)) (HPAB-AP491-YC-F(E))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, FuncS
Compare

Human Anti-αvβ6 Recombinant Antibody; Fab Fragment (HPAB-AP492-YC-F(E)) (HPAB-AP492-YC-F(E))
- Derivation: Humanized (mouse/human)
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, FuncS
Compare

Anti-human Integrin αvβ6 scFv Fragment (CSβ6) (TAB-756LC-S(P))
- Application: ELISA
Compare

Anti-human Integrin αvβ6 scFv Fragment (10D5) (TAB-757LC-S(P))
- Application: ELISA
Compare

Anti-human Integrin αvβ6 Recombinant Antibody (CSβ6) (TAB-756LC) (TAB-756LC)
- Application: FuncS, IHC
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Anti-human Integrin αvβ6 Recombinant Antibody (TAB-758LC) (TAB-758LC)
- Application: ELISA, FC
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SmartAb™ Recombinant Anti-Integrin αvβ6 pH-dependent Antibody (VS-0825-YC366) (VS-0825-YC366)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human, Cynomolgus, Mouse
- Type: Human IgG
- Application: ELISA, FC
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For Research Use Only. Not For Clinical Use.

Background

Integrin αvβ3 is a versatile integrin that recognizes a broad range of ECM ligands, including vitronectin, fibronectin, and osteopontin. It's involved in diverse processes such as angiogenesis, bone remodeling, and tumor progression. αvβ3 is particularly well-known for its role in promoting angiogenesis, the formation of new blood vessels, which is critical in both normal development and pathological conditions like cancer. This integrin has also been a target for therapies aimed at inhibiting tumor growth and metastasis.

The integrin αvβ6 is unique in that it is expressed exclusively in epithelial cells, and β6 partners only with αv forming a single heterodimer. During embryogenesis αvβ6 is expressed at high levels in the developing lung, skin and kidney epithelia and its expression is downregulated in healthy adult epithelia. However recent unpublished data from our laboratory suggest that αvβ6 is expressed at high levels in the adult hair follicles