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KARS1
Loading...Anti-KARS1 Products
- Anti-KARS1 Immunohistochemistry Kit (VS-0525-XY3710)
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- Species Reactivity: Human
- Target: KARS1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.