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KC-4

Anti-KC-4 Products
- Human Anti-KC-4 Recombinant Antibody (clone HuKC4V2) (HPAB-0057-YJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: IHC, RIA
- Human Anti-KC-4 Recombinant Antibody (clone HuKC4V2); scFv Fragment (HPAB-0057-YJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: IHC, RIA
- Human Anti-KC-4 Recombinant Antibody (clone HuKC4V2); Fab Fragment (HPAB-0057-YJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: IHC, RIA
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For Research Use Only. Not For Clinical Use.
Background
The antigen appears in two forms in carcinoma cells, only the smaller of these forms being expressed in the cell membrane. The second form occurs at a higher density of expression, is found both in the cytoplasm and the membrane of carcinoma cells and has an approximate 438 Kdalton molecular weight (range of 390, 000-450, 000). Labeled KC-4 was applied to the diagnosis and medical treatment of various carcinomas, particularly adenocarcinoma and squamous cell carcinoma regardless of the human organ site of origin.