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KCNF1
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For Research Use Only. Not For Clinical Use.
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008]
Protein class
Plasma proteins, Transporters, Voltage-gated ion channels
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Extravillous trophoblasts, Excitatory neurons, Inhibitory neurons, Syncytiotrophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (A549, MCF7, T-47d)
Interaction
Heteromultimer with KCNG3, KCNG4 and KCNV2. Interacts with DLG1.
Molecular function
Ion channel, Potassium channel, Voltage-gated channel
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