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KCNJ15
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For Research Use Only. Not For Clinical Use.
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Eight transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2013]
Protein class
FDA approved drug targets, Voltage-gated ion channels
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Proximal tubular cells, Alveolar cells type 2, Cholangiocytes, Alveolar cells type 1)
Immune cell specificity
Immune cell enriched (neutrophil)
Cell line specificity
Cell line enhanced (ASC TERT1, GAMG, HBEC3-KT, RPTEC TERT1, RT4)
Interaction
Interacts with PATJ.
Molecular function
Ion channel, Voltage-gated channel
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