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KLK11
Anti-KLK11 Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG3
- Application: WB, IF, IHC, IP
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
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For Research Use Only. Not For Clinical Use.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed. [provided by RefSeq, Dec 2016]
Protein class
Cancer-related genes, Enzymes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Late spermatids, Prostatic glandular cells, Club cells, Suprabasal keratinocytes, Urothelial cells, Squamous epithelial cells, Basal prostatic cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (EFO-21, HaCaT)
Molecular function
Hydrolase, Protease, Serine protease
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