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LGR4

Anti-LGR4 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway. This Wnt signaling pathway activation is necessary for proper development of many organs of the body.
Protein class

Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Astrocytes, Glandular and luminal cells, Syncytiotrophoblasts, Distal enterocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HAP1, RPTEC TERT1, U-2197)

Molecular function

Developmental protein, G-protein coupled receptor, Receptor, Transducer

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