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LRRK1

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Anti-LRRK1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a multi-domain protein that is a leucine-rich repeat kinase and a GDP/GTP binding protein. The encoded protein is thought to play a role in the regulation of bone mass. Mice lacking a similar gene showed severe osteopetrosis, increased bone mineralization and decreased bone resorption.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Microglial cells, Excitatory neurons)

Immune cell specificity

Immune cell enhanced (plasmacytoid DC)

Cell line specificity

Cell line enhanced (U-698)

Interaction

Homodimer.

Molecular function

Kinase, Serine/threonine-protein kinase, Transferase

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