Rabbit Anti-LRRK1 Recombinant Antibody (clone rN341/37) (CAT#: VS-0422-LC129)
The purified rabbit Anti-LRRK1 recombinant antibody (clone rN341/37) product displayed high specificity against the LRRK1 protein of human.
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Custom Production
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/if_selected.jpg
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/ihc_selected.jpg
(Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/ihc_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/26071_B_7_5.jpg
(Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/26071_B_7_5.jpg
Figure 4 Liver
(Cholangiocytes
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/26071_A_7_4.jpg
(Cholangiocytes
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/26071_A_7_4.jpg
Figure 5 Kidney
(Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/26071_A_8_5.jpg
(Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/26071_A_8_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/26071_A_6_6.jpg
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/26071_A_6_6.jpg
Figure 7 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/26071_A_9_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10537/26071_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enhanced (U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000154237-LRRK1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000154237-LRRK1
Specifications
- Immunogen
- LRRK1 epitope: amino acids 1695-2015 (C-terminus) of human LRRK1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human LRRK1
- Species Reactivity
- Human
- Clone
- rN341/37
- Applications
- ICC, WB, IF
- Conjugate
- Unconjugated
- Related Disease
- Osteosclerotic Metaphyseal Dysplasia and Metaphyseal Dysplasia
Product Property
- Purification
- Protein A purified
- Purity
- >95%
- Concentration
- 1 mg/mL
- Buffer
- PBS
- Storage
- Store at 4°C for short term. For long term storage, store at-20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Immunocytochemistry, Western Blot and Immunofluorescence.
Target
- Alternative Names
- OSMD; RIPK6; Roco1; leucine-rich repeat serine/threonine-protein kinase 1; EC 2.7.11.1
- Gene ID
- 79705
- UniProt ID
- Q38SD2
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0941-CN | Recombinant Mouse Anti-LRRK1 Monoclonal Antibody (5B1) | WB, IHC | Mouse IgG2b |
| VS-0422-LC127 | Mouse Anti-LRRK1 Recombinant Antibody (clone mN341/37) | ICC, WB, IF | Mouse IgG2a |
| VS-0422-LC128 | Human Anti-LRRK1 Recombinant Antibody (clone hN341/37) | ICC, WB, IF | Human IgG1 |
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For Research Use Only. Not For Clinical Use.
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