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MTX
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- Recombinant Anti-MTX Antibody (MOB-680)
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- Derivation: Mouse
- Type: IgG
- Application: ELISA, WB, FuncS
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- Mouse Anti-MTX Recombinant Antibody (clone AB119) (HPAB-0725-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Recombinant Human Anti-MTX Antibody (MHH-680)
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- Derivation: Human
- Type: IgG
- Application: ELISA, IP, FuncS
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- Mouse Anti-MTX Recombinant Antibody (HPAB-AP396-YC) (HPAB-AP396-YC)
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- Type: Mouse IgG
- Application: ECL
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- Mouse Anti-MTX Recombinant Antibody (HPAB-AP397-YC) (HPAB-AP397-YC)
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- Type: Mouse IgG
- Application: ECL
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- Mouse Anti-MTX Recombinant Antibody (HPAB-AP398-YC) (HPAB-AP398-YC)
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- Type: Mouse IgG
- Application: ECL
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- Mouse Anti-MTX Recombinant Antibody; scFv Fragment (HPAB-AP396-YC-S(P)) (HPAB-AP396-YC-S(P))
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- Type: Mouse scFv
- Application: ECL
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- Mouse Anti-MTX Recombinant Antibody; scFv Fragment (HPAB-AP397-YC-S(P)) (HPAB-AP397-YC-S(P))
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- Type: Mouse scFv
- Application: ECL
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- Recombinant Human Anti-MTX Antibody Fab Fragment (MHH-680-F(E))
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- Derivation: Human
- Type: Fab
- Application: IP, Neut, FuncS
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- Recombinant Human Anti-MTX Antibody scFv Fragment (MHH-680-S(P))
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- Derivation: Human
- Type: scFv
- Application: ELISA, WB, FuncS
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- Mouse Anti-MTX Recombinant Antibody; scFv Fragment (HPAB-AP398-YC-S(P)) (HPAB-AP398-YC-S(P))
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- Type: Mouse scFv
- Application: ECL
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- Mouse Anti-MTX Recombinant Antibody; Fab Fragment (HPAB-AP396-YC-F(E)) (HPAB-AP396-YC-F(E))
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- Type: Mouse Fab
- Application: ECL
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- Mouse Anti-MTX Recombinant Antibody; Fab Fragment (HPAB-AP397-YC-F(E)) (HPAB-AP397-YC-F(E))
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- Type: Mouse Fab
- Application: ECL
Compare
- Mouse Anti-MTX Recombinant Antibody; Fab Fragment (HPAB-AP398-YC-F(E)) (HPAB-AP398-YC-F(E))
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- Type: Mouse Fab
- Application: ECL
Compare
- Mouse Anti-MTX Recombinant Antibody (clone AB119); Fab Fragment (HPAB-0725-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-MTX Recombinant Antibody (clone AB119); scFv Fragment (HPAB-0725-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
Compare
- Recombinant Anti-MTX Antibody Fab Fragment (MOB-680-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: WB, IP, FuncS
Compare
- Recombinant Anti-MTX Antibody scFv Fragment (MOB-680-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: ELISA, WB, IF, FuncS
Compare
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For Research Use Only. Not For Clinical Use.
Methotrexate (MTX) is a clinically important antifolate drug, which competitively inhibits dihydrofolate reductase (DHFR), thereby impairing folate production. Folate is necessary for the de novo synthesis of thymidine, required for DNA synthesis. Folate is also required for purine base synthesis of DNA, RNA, thymidylates, and proteins. Thus, methotrexate impairs synthesis of thymidine and other metabolites crucial for cell proliferation.