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For Research Use Only. Not For Clinical Use.
Plasma proteins, Transcription factors
Intracellular
Group enriched (dendritic cells, NK-cells, T-cells, Plasma cells, Spermatocytes)
Immune cell enhanced (gdT-cell, MAIT T-cell)
Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, Daudi, HBF TERT88)
Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.
Activator, DNA-binding