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MYF5

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For Research Use Only. Not For Clinical Use.


MYF5 (Myogenic Factor 5) is a Protein Coding gene. Diseases associated with MYF5 include Rhabdomyosarcoma and Skeletal Muscle Cancer. Among its related pathways are miRs in Muscle Cell Differentiation and Myogenesis. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is MYOD1.
Protein class

Disease related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Skeletal myocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (LHCN-M2)

Interaction

Efficient DNA binding requires dimerization with another bHLH protein.

Molecular function

Activator, Developmental protein, DNA-binding

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