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NC-GC

Anti-NC-GC Products
- Recombinant Human Anti-NC-GC Soluble TCR (Vα24Vβ11) (KIH) (VS-0622-YF7430)
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- Epitope: Naphthylcarba-GalCer
- MHC: human CD1d
- Recombinant Mouse Anti-NC-GC Soluble TCR (Vα14Vβ8.2) (KIH) (VS-0622-YF7429)
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- Epitope: Naphthylcarba-GalCer
- MHC: mouse CD1d
- Recombinant Human Anti-NC-GC Soluble TCR (Vα24Vβ11) (C-Cys) (VS-0622-YF4722)
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- Epitope: Naphthylcarba-GalCer
- MHC: human CD1d
- Recombinant Mouse Anti-NC-GC Soluble TCR (Vα14Vβ8.2) (C-Cys) (VS-0622-YF4721)
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- Epitope: Naphthylcarba-GalCer
- MHC: mouse CD1d
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- Epitope: Naphthylcarba-GalCer
- MHC: human CD1d
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- Epitope: Naphthylcarba-GalCer
- MHC: mouse CD1d
- Human Anti-NC-GC Recombinant Soluble TCR (clone Vα24Vβ11) (scTCR-0715YC-S(P))
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- Epitope: Naphthylcarba-GalCer
- MHC: human CD1d
- Mouse Anti-NC-GC Recombinant Soluble TCR (clone Vα14Vβ8.2) (scTCR-0714YC-S(P))
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- Epitope: Naphthylcarba-GalCer
- MHC: mouse CD1d
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For Research Use Only. Not For Clinical Use.
Background
GCK127 and GCK152 have their O-glycosidic linkages replaced with an E-alkene linker between the sugar and lipid moieties, reminiscent of C-glycoside (-C-GalCer), whereas GCK152 also has a truncated fatty acid with a terminal phenyl group. Naphthylcarba-GalCer (NC-GC) has an aromatic 6-OH galactose modification, similar to the previously crystallized naphthylurea (NU)-GC. However, unlike NU-GC where the naphthyl is linked via a urea group, NC-GC has a carbamate linker, which provides more flexibility to the naphthyl moiety.