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NCR3
Loading...Anti-NCR3 Products
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- Species Reactivity: Rhesus monkey, Cynomolgus monkey
- Type: Mouse IgG1
- Application: Activ, FuncS
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- Mouse Anti-NCR3 Recombinant Antibody (VS3-FY2768) (VS3-FY2768)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB, IHC, FC, ELISA
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- Mouse Anti-NCR3 Agonistic Antibody (VS-0724-XY38) (VS-0724-XY38)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: FC, Agonistic assays, CyTOF®
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- Recombinant Mouse Anti-NCR3 Antibody (NEUT-1763CQ) (NEUT-1763CQ)
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- Species Reactivity: Human
- Type: IgG1, κ
- Application: FC, ELISA, BL
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
Protein class
CD markers
Predicted location
Membrane
Single cell type specificity
Group enriched (NK-cells, dendritic cells, T-cells, B-cells)
Immune cell specificity
Immune cell enhanced (MAIT T-cell)
Cell line specificity
Cell line enhanced (Daudi, HEL, NB-4, U-698)
Interaction
Homodimer in the unliganted form. Interacts with CD3Z. Interacts with and is activated by binding to NCR3LG1. Interacts with and is activated by binding to BAG6.
Molecular function
Receptor
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