NLGN1

AbPlus Recombinant Antibody Products Formats

Anti-NLGN1 Recombinant Antibody Products

Anti-NLGN1 Immunohistochemistry Kit (VS-0325-XY1497)
- Species Reactivity: Human, Mouse, Rat
- Target: NLGN1
- Application: IHC
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For Research Use Only. Not For Clinical Use.

NLGN1 (Neuroligin 1) is a Protein Coding gene. This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Diseases associated with NLGN1 include Autism 20 and Pervasive Developmental Disorder.

Protein class

Disease related genes, Human disease related genes, Potential drug targets, Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Oligodendrocyte precursor cells, Inhibitory neurons, Excitatory neurons, Oligodendrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (fHDF/TERT166, HUVEC TERT2, RH-30, WM-115)

Interaction

Interacts with NRXN1, NRXN2 and NRXN3. Interacts with NLGN3. Interacts with AIP1 and PDZRN3 (By similarity). Interacts (via its C-terminus) with DLG4/PSD-95 (via PDZ domain 3). Interacts with GOPC.

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