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ONECUT1
Loading...Anti-ONECUT1 Products
- Anti-ONECUT1 Immunohistochemistry Kit (VS-0525-XY5087)
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- Species Reactivity: Human
- Target: ONECUT1
- Application: IHC
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- Anti-Mouse ONECUT1 Immunohistochemistry Kit (VS-0525-XY5088)
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- Species Reactivity: Human, Mouse, Rat
- Target: ONECUT1
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Horizontal cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, Hep G2, MCF7, NTERA-2, SuSa, WM-115)
Interaction
Binds DNA as a monomer.
Molecular function
Activator, DNA-binding
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