PEAK1

Formats

Anti-PEAK1 Recombinant Antibody Products

Recombinant Mouse anti-Human PEAK1 Monoclonal antibody (EML1880) (MOB-0224CT)
- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.

This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014]

Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocyte precursor cells, Oligodendrocytes, Excitatory neurons, Alveolar cells type 1)

Immune cell specificity

Immune cell enriched (NK-cell)

Cell line specificity

Cell line enhanced (TIME)

Interaction

Homodimer (PubMed:29212708). Interacts with BCAR1 and CRK (PubMed:20534451). Interacts with PRAG1 (PubMed:29079850). Interacts (when phosphorylated at Tyr-1188) with SHC1 (via PID domain) (PubMed:23846654). Found in a complex with PPP1CA, PPP1CC, SHC1 and PEAK1.

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