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PIGO

Formats

Anti-PIGO Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Protein class

Disease related genes, Human disease related genes, Metabolic proteins

Predicted location

Membrane

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Forms a complex with PIGF. PIGF is required to stabilize PIGO (By similarity).

Molecular function

Transferase

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