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PIVKA-II
Loading...Anti-PIVKA-II Products
- Human Anti-PIVKA-II Recombinant Antibody; Fab Fragment (TAB-1030CL-F(E)) (TAB-1030CL-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Recombinant Mouse Anti-PIVKA-II Antibody (P5) (MOB-077LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Human Anti-PIVKA-II Antibody, mRNA (TAB-772CL-mRNA)
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- Species Reactivity: Human
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- Mouse Anti-PIVKA-II Recombinant Antibody; Fab Fragment (TAB-1031CL-F(E)) (TAB-1031CL-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
Background
Des-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. Normally, the prothrombin precursor undergoes post-translational carboxylation (addition of a carboxylic acid group) by gamma-glutamyl carboxylase in the liver prior to secretion into plasma. DCP/PIVKA-II may be detected in people with deficiency of vitamin K (due to poor nutrition or malabsorption) and in those taking warfarin or other medication that inhibits the action of vitamin K.