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POLR3B
Anti-POLR3B Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, RNA polymerase related proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Inhibitory neurons)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
Molecular function
Nucleotidyltransferase, Transferase
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