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PPP1R14A
Anti-PPP1R14A Recombinant Antibody Products
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Sertoli cells, Peritubular cells, Smooth muscle cells, Granulosa cells, Leydig cells, Adipocytes)
Immune cell specificity
Group enriched (memory B-cell, naive B-cell, plasmacytoid DC)
Cell line specificity
Group enriched (A549, EFO-21, K-562)
Molecular function
Protein phosphatase inhibitor
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