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PRP4K

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For Research Use Only. Not For Clinical Use.


Background

Serine/threonine kinase involved in spliceosomal assembly as well as mitosis and signaling regulation.
Connects chromatin mediated regulation of transcription and pre-mRNA splicing.
During spliceosomal assembly, interacts with and phosphorylates PRPF6 and PRPF31, components of the U4/U6-U5 tri-small nuclear ribonucleoprotein (snRNP), to facilitate the formation of the spliceosome B complex.
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