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PSMA4
Loading...Anti-PSMA4 Products
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, IF, IP
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- AbPlus™ Anti-PSMA4 Magnetic Beads (VS-0724-YC916) (VS-0724-YC916)
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- Target: PSMA4
- Target Species: Human
- Application: IP, Protein Purification
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- Mouse Anti-NHP PSMA4 Recombinant Antibody (clone OTI4B8) (VS-1024-XY417)
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- Species Reactivity: Human, Mouse, Non-human primate, Rat
- Type: Mouse IgG1
- Application: WB, IHC
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- Anti-PSMA4 Immunohistochemistry Kit (VS-0325-XY1778)
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- Species Reactivity: Human, Mouse, Rat
- Target: PSMA4
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a core alpha subunit of the 20S proteosome, which is a highly ordered ring-shaped structure composed of four rings of 28 non-identical subunits. Proteasomes cleave peptides in an ATP- and ubiquitin-dependent manner.
Protein class
Enzymes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings. The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits. The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7. (Microbial infection) Interaction with HTLV-1 TAX protein favors NFKB1 activation.
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