PTGS1

Recombinant Antibody Products Formats

Anti-PTGS1 Recombinant Antibody Products

Hi-Affi™ Recombinant Rabbit Anti-PTGS1 Monoclonal Antibody (DS2921AB) (MOR-2921)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP, IHC-P, ICC/IF, FC
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For Research Use Only. Not For Clinical Use.

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression.

Protein class

Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (granulocytes, Glandular and luminal cells, Endometrial ciliated cells, Hepatic stellate cells, Suprabasal keratinocytes, Macrophages)

Immune cell specificity

Immune cell enhanced (basophil)

Cell line specificity

Cell line enhanced (ASC diff, ASC TERT1, BJ, BJ hTERT+, HEL, HMC-1)

Interaction

Homodimer.

Molecular function

Dioxygenase, Oxidoreductase, Peroxidase

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