PTS

Recombinant Antibody Products Formats

Anti-PTS Recombinant Antibody Products

Hi-Affi™ Recombinant Rabbit Anti-PTS Monoclonal Antibody (DS2938AB) (MOR-2938)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ICC/IF, IHC-P, IP, WB
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For Research Use Only. Not For Clinical Use.

The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.

Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homohexamer formed of two homotrimers in a head to head fashion.

Molecular function

Lyase

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