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RABEP1
Anti-RABEP1 Recombinant Antibody Products
- AbPlus™ Anti-RABEP1 Magnetic Beads (VS-0724-YC187) (VS-0724-YC187)
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- Target: RABEP1
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
RABEP1 (Rabaptin, RAB GTPase Binding Effector Protein 1) is a Protein Coding gene. Diseases associated with RABEP1 include Tuberous Sclerosis 2. Among its related pathways are Delta508-CFTR traffic/Sorting endosome formation in CF and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and growth factor activity. An important paralog of this gene is RABEP2.
Protein class
Cancer-related genes
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer when bound to RAB5A (PubMed:15378032). Heterodimer with RABGEF1 (PubMed:11452015, PubMed:9323142). The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding (PubMed:10698684, PubMed:8521472, PubMed:20098723, PubMed:12773381). Interacts with TSC2 (PubMed:9045618). Interacts with GGA1 (via GAE domain), GGA2 (via GAE domain) and GGA3 (via GAE domain) (PubMed:12505986, PubMed:14665628). Interacts with AP1G1 (via GAE domain) (PubMed:12505986, PubMed:12773381, PubMed:14665628). Interacts with AP1G2 (via GAE domain) (PubMed:12505986, PubMed:14665628). Interacts with ECPAS (PubMed:20682791). Interacts with KCNH1 (By similarity). Interacts with PKD1 (via C-terminal domain) and GGA1; the interactions recruit PKD1:PKD2 complex to GGA1 and ARL3 at trans-Golgi network (By similarity). Interacts with KCNH1 (By similarity).
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