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RALGDS

Anti-RALGDS Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, IF, IP
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For Research Use Only. Not For Clinical Use.
Background
Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.
Protein class
RAS pathway related proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Urothelial cells)
Immune cell specificity
Group enriched (gdT-cell, T-reg, memory CD8 T-cell, memory CD4 T-cell, MAIT T-cell, naive CD8 T-cell, NK-cell)
Cell line specificity
Cell line enhanced (HDLM-2, SH-SY5Y)
Interaction
Interacts with RIT1 and RIT2 (By similarity). Interacts with OOG1 (By similarity). Interacts with TRAF3 (PubMed:27438768). Interacts with HRAS (By similarity).
Molecular function
Guanine-nucleotide releasing factor
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