Human disease related genes, RAS pathway related proteins
Intracellular
Cell type enhanced (dendritic cells)
Immune cell enhanced (basophil)
Low cell line specificity
Interacts with MAP1S (PubMed:15205320, PubMed:15753381). Interacts with XPA (PubMed:10888881). Binds to the N-terminal of CDC20 during prometaphase (PubMed:14743218). Binds to STK3/MST2 and STK4/MST1 (PubMed:15109305, PubMed:16510573, PubMed:21199877). Recruited to the TNFRSF1A and TNFRSF10A complexes in response to their respective cognate ligand, after internalization (PubMed:15949439). Can self-associate (PubMed:11857081). Part of a complex with MDM2, DAXX, RASSF1 and USP7 (PubMed:18566590). Interacts with ECM2 (By similarity). [Isoform A]: Interacts with MOAP1 (PubMed:15949439). Interacts with E4F1 (PubMed:14729613). Interacts with RSSF5 and probably associates with HRAS via a RSSF1 isoform A-RSSF5 heterodimer (PubMed:11857081). Interacts (via C-terminus) with DAXX (via N-terminus); the interaction is independent of MDM2 and TP53 (PubMed:18566590). Interacts (via N-terminus) with MDM2 (via C-terminus); the interaction is independent of TP53 (PubMed:18566590). Interacts with RAB39A (By similarity). Interacts with RAB39B; the interaction is weak (By similarity). [Isoform C]: Interacts (via N-terminus) with DAXX (PubMed:18566590). Interacts with RAB39B; the interaction is strong (By similarity). Does not interact with RAB39A (By similarity). [Isoform H]: Interacts (via N-terminus) with DAXX.
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.