RGS12

AbPlus Recombinant Antibody Products

Anti-RGS12 Recombinant Antibody Products

Anti-RGS12 Immunohistochemistry Kit (VS-0325-XY1910)
- Species Reactivity: Human, Mouse, Rat
- Target: RGS12
- Application: IHC
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For Research Use Only. Not For Clinical Use.

This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined.

Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Inhibitory neurons, Urothelial cells, Basal prostatic cells, Suprabasal keratinocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with GNAI1 (PubMed:18434541). Interacts with GNAI2 and GNAI3; the interactions are GDP-dependent (By similarity).

Molecular function

GTPase activation, Repressor, Signal transduction inhibitor

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