


RIN1

Anti-RIN1 Products
- Mouse Anti-RIN1 Recombinant Antibody (clone 1H4) (MOB-3200z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG2b
- Application: WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
RAS pathway related proteins
Intracellular
Cell type enhanced (Basal respiratory cells, Basal squamous epithelial cells, Squamous epithelial cells)
Immune cell enhanced (non-classical monocyte)
Cell line enhanced (hTCEpi, U-2197)
Interacts with the GTP-bound form of Ras proteins (NRAS, HRAS and KRAS). This interaction prevents the association between RAF1 and Ras. Interacts with 14-3-3 proteins YWHAB, YWHAE and YWHAZ when phosphorylated on Ser-351. Interacts with the SH3 domain of ABL1 and ABL2. Interacts with RAB5A. The interaction with Ras is probably regulated and antagonized by the interaction with 14-3-3 proteins. The interaction with 14-3-3 proteins is regulated by phosphorylation on Ser-351.
GTPase activation