Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets
Intracellular
Cell type enhanced (Langerhans cells)
Low immune cell specificity
Low cell line specificity
Interacts with AFDN, the C-terminal domain of RALGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form. Strongly interacts with BRAF, but only weakly with RAF1. BARF and RAF1 association is dependent upon the GTP-bound state. Interacts with RGL3 (By similarity).
Hydrolase
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For Research Use Only. Not For Clinical Use.