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    RNGTT

    Formats

    Anti-RNGTT Recombinant Antibody Products

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    For Research Use Only. Not For Clinical Use.


    RNGTT (RNA Guanylyltransferase And 5'-Phosphatase) is a Protein Coding gene. Diseases associated with RNGTT include Lymphomatous Meningitis and Cecum Adenocarcinoma. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Gene Ontology (GO) annotations related to this gene include GTP binding and protein tyrosine phosphatase activity. An important paralog of this gene is DUSP11.
    Protein class

    Enzymes, Metabolic proteins, Plasma proteins

    Predicted location

    Intracellular

    Single cell type specificity

    Cell type enhanced (Inhibitory neurons, Excitatory neurons, Oligodendrocyte precursor cells, Oligodendrocytes)

    Immune cell specificity

    Low immune cell specificity

    Cell line specificity

    Low cell line specificity

    Interaction

    Interacts with POLR2A (via C-terminus); this enhances guanylyltransferase activity. Binds (via GTase domain) to the elongating phosphorylated form of RNA polymerase II; can form direct interactions with the phosphorylated POLR2A C-terminal domain and indirect interactions via bound RNA (By similarity). Interacts with SUPT5H and RNMT. Interacts with HIV-1 Tat. (Microbial infection) Interacts with HIV-1 Tat.

    Molecular function

    Hydrolase, Multifunctional enzyme, Nucleotidyltransferase, Protein phosphatase, Transferase

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