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RORB
Loading...Anti-RORB Products
- Rabbit Anti-RORB Recombinant Antibody (VS13-YC1015) (VS13-YC1015)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB
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- Anti-RORB Immunohistochemistry Kit (VS-0525-XY6180)
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- Species Reactivity: Human
- Target: RORB
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]
Protein class
Disease related genes, Human disease related genes, Nuclear receptors, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Horizontal cells, Endometrial stromal cells, Astrocytes, Muller glia cells, Rod photoreceptor cells, Excitatory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HHSteC, HSkMC, JURKAT, MOLT-4, SH-SY5Y)
Interaction
Monomer. Interacts with CRX.
Molecular function
Activator, Developmental protein, DNA-binding, Receptor
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