RUNX3

AbPlus Formats

Anti-RUNX3 Recombinant Antibody Products

CytoStream™ Mouse Anti-RUNX3 Recombinant Antibody (clone R3-5G4) (VS-0225-XY190)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, kappa
- Application: FC
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Anti-RUNX3 Immunohistochemistry Kit (VS-0325-XY1979)
- Species Reactivity: Human, Mouse, Rat
- Target: RUNX3
- Application: IHC
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For Research Use Only. Not For Clinical Use.

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]