Anti-S1PR1 Recombinant Antibody Products

Loading...

Anti-S1PR1 Products

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.

The crucial regulatory function of S1PR1 in immune diseases establishes it as an excellent target for therapy. Creative Biolabs provides a series of anti-S1PR1 recombinant antibodies to expedite research and development of therapeutics. Our established recombinant antibody technology optimizes these antibodies to deliver superior specificity and reactivity in various applications.

S1PR1: A Promising Target for Immunomodulatory Therapy

A member of the G protein-coupled receptor (GPCR) family, S1PR1 (sphingosine-1-phosphate receptor 1) is essential in controlling important physiological processes, including immune cell motility. An important process driving immune surveillance is the transfer of lymphocytes from lymphoid organs to systemic circulation, controlled by this receptor. Apart from its immunological function, S1PR1 affects oncogenesis and cardiovascular pathology, maintenance of endothelial barrier integrity, and helps in vascular morphogenesis. The rise of this receptor as a therapeutic target in autoimmune diseases has been driven by its effect on lymphocyte trafficking.

Alternative Names

Sphingosine-1-phosphate receptor 1; S1P receptor 1; S1PR1; EDG1; EDG-1; endothelial differentiation gene 1; CD363; CHEDG1; D1S3362; ECGF1.

Background

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.

Anti-S1PR1 rAb Products

Creative Biolabs provides high-quality anti-S1PR1 recombinant antibodies, produced using advanced recombinant DNA technology to guarantee exceptional consistency, specificity, and purity for reliable research applications. These priceless instruments enable scientists to explore in great detail the expression, function, and signaling pathways of the sphingosine-1-phosphate receptor 1 in many different cellular and disease models. By focusing on S1PR1, these antibodies enable researchers to clarify its complicated involvement in physiological processes like immune cell trafficking and vascular biology, therefore advancing our knowledge of this important receptor and its consequences in many disease conditions.

Table 1. Featured anti-S1PR1 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs implements stringent quality assurance protocols for the anti-S1PR1 recombinant antibodies, maintaining elevated benchmarks for batch-to-batch purity, target specificity, and reproducibility. These evaluations incorporate methodologies such as SDS-PAGE, WB, ELISAs, etc., to assess structural integrity, target-binding efficacy, and cross-reactivity thresholds. By adhering to this systematic validation framework, we guarantee researchers access to reagents characterized by reproducibility and reliability, essential for advancing mechanistic and translational studies of S1PR1 signaling.

Customer Reviews

Excellent

An***a
Rabbit Anti-S1PR1 Recombinant Antibody (clone 4F2) (ZG-0557U)

For our in vitro lymphocyte migration tests, we have been utilizing Creative Biolabs' anti-S1PR1 antibody; the findings have been repeatedly consistent. The antibody has outstanding selectivity and shows very little off-target binding in our hands. Common problem with certain antibody providers, batch-to-batch variance, has been almost nonexistent with this product. Our constant research depends on this consistency, which has also helped us save a lot of time and money in troubleshooting.

22/Nov/2023

Excellent

Me***y
Recombinant Mouse Anti-Human S1PR1 Antibody (MOB-2356MZ)

The anti-S1PR1 recombinant antibody worked beautifully for our immunofluorescence studies on human tissue samples. We observed clear and specific staining of S1PR1, with minimal background noise. The signal was consistent across different batches, making it a reliable reagent for our experiments investigating S1PR1 expression patterns.

1/Dec/2023

Excellent

Vi***a
Rabbit Anti-S1PR1 Recombinant Antibody (clone JM10-66) (VS3-WK544)

The high purity of Creative Biolabs' recombinant anti-S1PR1 antibody is evident in our immunostaining experiments. We've achieved clear and specific labeling of S1PR1 on various cell types, with low background noise. The accompanying technical data sheet was comprehensive and provided helpful guidance for optimizing our staining protocols. Overall, this antibody has proven to be a robust and dependable tool for our studies on S1PR1 expression.

5/May/2024

rAb Production

As a globally trusted partner, Creative Biolabs provides researchers worldwide with a dependable and consistent source of high-quality anti-S1PR1 recombinant antibodies. Leveraging advanced recombinant technologies, our meticulously developed and validated antibodies ensure exceptional quality and performance across diverse research applications. We are dedicated to facilitating scientific advancement by equipping researchers with the reliable reagents needed to explore the intricacies of S1PR1 signaling in various biological contexts.

Featured Anti-S1PR1 Recombinant Antibody Production Platforms
Fig.2 Milligram-scale anti-S1PR1 recombinant antibody production.

Fig.3 Gram-scale anti-S1PR1 recombinant antibody production.

rAb Modalities

Creative Biolabs offers top-notch, custom anti-S1PR1 recombinant antibodies, tailored precisely to meet the diverse needs of researchers all over the world.

Fig.4 Full-length anti-S1PR1 recombinant antibody production and modalities.

S1PR-Targeted Drug Information-1

Table 2. Public drug targeting S1PR.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

S1PR-Targeted Drug Information-2

Table 3. Drug targeting S1PR (under development).

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Drawing upon our extensive expertise in antibody development and production, Creative Biolabs offers high-quality S1PR1 recombinant antibodies that deliver consistently outstanding results for diverse research applications. We prioritize the reliability and performance of our antibodies and invite researchers investigating the crucial role of S1PR1 to contact us for customized pricing that suits their unique research requirements.