Enzymes, Plasma proteins
Intracellular
Cell type enhanced (Cone photoreceptor cells)
Not detected in immune cells
Low cell line specificity
Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10 (PubMed:15960975). Interacts with EP300, NPM1 and CDCA8 (PubMed:19015314, PubMed:18946085, PubMed:18259216, PubMed:19680224). Component of the 5FMC complex, at least composed of PELP1, LAS1L, TEX10, WDR18 and SENP3; the complex interacts with methylated CHTOP and ZNF148 (PubMed:22872859). Interacts with NOL9 (By similarity). Interacts with CCAR2 (PubMed:25406032).
Hydrolase, Protease, Thiol protease
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For Research Use Only. Not For Clinical Use.