


SERPINB1

Anti-SERPINB1 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, IP, IF, ELISA
- AbPlus™ Anti-SERPINB1 Magnetic Beads (VS-0724-YC879) (VS-0724-YC879)
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- Target: SERPINB1
- Target Species: Human
- Application: IP, Protein Purification
- Mouse Anti-NHP SERPINB1 Recombinant Antibody (clone OTI1D1) (VS-1024-XY469)
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- Species Reactivity: Dog, Human, Non-human primate
- Type: Mouse IgG2a
- Application: WB, ICC, FC
- Anti-SERPINB1 Immunohistochemistry Kit (VS-0525-XY6478)
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- Species Reactivity: Human
- Target: SERPINB1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Plasma proteins
Intracellular, Secreted (different isoforms)
Cell type enhanced (Exocrine glandular cells, Pancreatic endocrine cells, Urothelial cells)
Low immune cell specificity
Cell line enhanced (CAPAN-2, OE19, U-937)
Monomer (PubMed:23269243). Interacts (via C-terminus) with CASP1; CASP4 (via CARD domain) and CASP5; these interactions regulate the activity of inflammatory caspases (PubMed:30692621). Interacts with PRTN3 (PubMed:30692621). Interacts with GZMH (PubMed:23269243).
Protease inhibitor, Serine protease inhibitor