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SH2B2

Anti-SH2B2 Products

Recombinant Mouse Anti-SH2B2 Antibody (clone 5E11G7) (VS3-FY1331)
- Type: Mouse IgG2b
- Application: ELISA, IHC, FC
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For Research Use Only. Not For Clinical Use.

Background

The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009]