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SHM
Anti-SHM Recombinant Antibody Products
- Recombinant Anti-SHM Antibody (MOB-903)
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- Derivation: Mouse
- Type: IgG
- Application: WB, ELISA, IHC, FuncS
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- Recombinant Human Anti-SHM Antibody (MHH-903)
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- Derivation: Human
- Type: IgG
- Application: RIA, IF, FuncS
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- Recombinant Human Anti-SHM Antibody Fab Fragment (MHH-903-F(E))
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- Derivation: Human
- Type: Fab
- Application: ELISA, WB, FC, FuncS
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- Recombinant Human Anti-SHM Antibody scFv Fragment (MHH-903-S(P))
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- Derivation: Human
- Type: scFv
- Application: ELISA, WB, FC, FuncS
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- Recombinant Anti-SHM Antibody Fab Fragment (MOB-903-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: IF, FACS, FuncS
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- Recombinant Anti-SHM Antibody scFv Fragment (MOB-903-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: ELISA, WB, Neut, FuncS
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For Research Use Only. Not For Clinical Use.
Somatic hypermutation is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it, as seen during class switching. A major component of the process of affinity maturation, SHM diversifies B cell receptors used to recognize foreign elements and allows the immune system to adapt its response to new threats during the lifetime of an organism. Somatic hypermutation involves a programmed process of mutation affecting the variable regions of immunoglobulin genes. Unlike germline mutation, SHM affects only individual immune cells, and the mutations are not transmitted to offspring.