+ Filter
Loading...
SHM
Loading...Anti-SHM Products
- Recombinant Anti-SHM Antibody (MOB-903)
-
- Derivation: Mouse
- Type: IgG
- Application: WB, ELISA, IHC, FuncS
Compare
- Recombinant Human Anti-SHM Antibody (MHH-903)
-
- Derivation: Human
- Type: IgG
- Application: RIA, IF, FuncS
Compare
- Recombinant Anti-SHM Antibody scFv Fragment (MOB-903-S(P))
-
- Derivation: Mouse
- Type: scFv
- Application: ELISA, WB, Neut, FuncS
Compare
- Recombinant Human Anti-SHM Antibody scFv Fragment (MHH-903-S(P))
-
- Derivation: Human
- Type: scFv
- Application: ELISA, WB, FC, FuncS
Compare
- Recombinant Human Anti-SHM Antibody Fab Fragment (MHH-903-F(E))
-
- Derivation: Human
- Type: Fab
- Application: ELISA, WB, FC, FuncS
Compare
- Recombinant Anti-SHM Antibody Fab Fragment (MOB-903-F(E))
-
- Derivation: Mouse
- Type: Fab
- Application: IF, FACS, FuncS
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
Somatic hypermutation is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it, as seen during class switching. A major component of the process of affinity maturation, SHM diversifies B cell receptors used to recognize foreign elements and allows the immune system to adapt its response to new threats during the lifetime of an organism. Somatic hypermutation involves a programmed process of mutation affecting the variable regions of immunoglobulin genes. Unlike germline mutation, SHM affects only individual immune cells, and the mutations are not transmitted to offspring.