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For Research Use Only. Not For Clinical Use.
Background
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (T-cells, B-cells, dendritic cells, Plasma cells)
Immune cell specificity
Group enriched (T-reg, memory CD4 T-cell, memory CD8 T-cell, memory B-cell, plasmacytoid DC, MAIT T-cell, naive B-cell, naive CD4 T-cell, naive CD8 T-cell, gdT-cell)
Cell line specificity
Group enriched (Daudi, HDLM-2, JURKAT, U-698)
Interaction
Homodimer; disulfide-linked. When phosphorylated, interacts with PTPN11/SHP2, GRB2 and CSK.
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