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SLC6A2

Anti-SLC6A2 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
- Rabbit Anti-SLC6A2 Recombinant Antibody (VS-0223-WK49) (VS-0223-WK49)
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- Derivation: Rabbit
- Species Reactivity: Rat, Mouse
- Type: Rabbit IgG
- Application: IHC
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- Species Reactivity: Rat, Mouse
- Target: SLC6A2
- Host Animal: Rabbit
- Application: ELISA, FC, Cell-uptake
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For Research Use Only. Not For Clinical Use.
Background
Enables neurotransmitter transmembrane transporter activity and norepinephrine:sodium symporter activity. Involved in neurotransmitter reuptake and norepinephrine uptake. Acts upstream of or within neurotransmitter transport and response to pain. Predicted to be located in cell surface. Predicted to be active in axon; neuronal cell body membrane; and presynaptic membrane. Is expressed in several structures, including adrenal gland; lip; nervous system; renal pelvis; and sensory organ. Used to study heart conduction disease. Human ortholog(s) of this gene implicated in alcohol dependence; hypertension; and neurocirculatory asthenia. Orthologous to human SLC6A2 (solute carrier family 6 member 2).
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Group enriched (Spermatocytes, Extravillous trophoblasts, Syncytiotrophoblasts, Late spermatids, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (SH-SY5Y)
Interaction
Interacts with PRKCABP.
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