Anti-SLC7A5 Recombinant Antibody Products

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Anti-SLC7A5 Products

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For Research Use Only. Not For Clinical Use.

At Creative Biolabs, we offer cutting-edge recombinant antibodies targeting SLC7A5, crucial for advancing biomedical research. Our advanced platforms guarantee that every product meets the highest standards of quality and performance. We are dedicated to accelerating scientific discovery by providing a wide range of reliable recombinant products, each designed to deliver exceptional value. In addition to our top-tier antibodies, we are committed to providing outstanding technical support, guiding researchers throughout every phase of their projects. Partnering with us means gaining not just innovative solutions but a reliable ally in your research journey.

SLC7A5: A Potential Therapeutic Target in Cancer Neurological and Metabolic Diseases

SLC7A5, or LAT1, is a key transporter for large neutral amino acids, playing an essential role in cellular metabolism. Its overexpression is commonly observed in cancer, where it supports the high nutritional demands of rapidly growing tumor cells. By facilitating amino acid uptake, SLC7A5 promotes tumor cell survival, growth, and resistance to therapies. As a result, targeting this transporter is being explored as a way to starve tumors and inhibit their progression. In neurological diseases, dysfunction of SLC7A5 can disrupt amino acid balance in the brain, contributing to conditions like Alzheimer's disease and epilepsy. Moreover, altered SLC7A5 activity is linked to metabolic disorders, where impaired amino acid transport affects normal cellular functions. Due to its involvement in these disease mechanisms, SLC7A5 is emerging as a promising therapeutic target, with potential treatments aimed at regulating its activity to improve outcomes in cancer, neurological, and metabolic diseases.

Alternative Names

Complement SLC7A5; solute carrier family 7 (amino acid transporter light chain, L system), member 5; E16; CD98; LAT1; 4F2LC; MPE16; hLAT1; D16S469E; large neutral amino acids transporter small subunit 1; 4F2 LC; 4F2 light chain; CD98 light chain; integral membrane p

Background

SLC7A5, also known as LAT1 (L - type amino acid transporter 1), is a member of the solute carrier family of membrane - bound transporters. It is a heterodimeric protein that forms a complex with 4F2hc (SLC3A2) to function as an amino acid transporter. Structurally, SLC7A5 has 12 transmembrane domains, and the heterodimeric complex is essential for its proper trafficking to the cell membrane and substrate recognition.

Anti-SLC7A5 rAb Products

Our goal is to advance scientific discovery by offering high-quality anti-SLC7A5 recombinant antibodies, delivering outstanding performance and dependable technical support to assist researchers at every stage of their work.

Customer Reviews

Excellent

K**in
Mouse Anti-SLC7A5 Recombinant Antibody (clone 98-3H3) (CAT#: HPAB-0247-WJ)

We used it in ELISA and western blot experiments with lysates from human glioblastoma cells. The antibody showed good specificity and consistent signal, with minimal background. It worked well under our standard conditions and helped validate SLC7A5 expression levels.

16/Mar/2024

Excellent

B**ra
Human Anti-SLC7A5 Recombinant Antibody (clone EP3-1) (CAT#: FAMAB-1260CQ)

We evaluated it using IP and IF in HeLa and U87 cells. In IP, the antibody showed strong target enrichment with minimal non-specific binding and consistent performance. For IF, it produced clear membrane labeling that aligned with known SLC7A5 expression. The antibody worked smoothly with standard protocols and required little adjustment. Overall, it's a reliable reagent for SLC7A5 detection in human cell studies.

13/Sep/2024

rAb Production

With extensive experience in recombinant antibody development and refinement, we are committed to delivering top-quality products with fast turnaround times. Our focus on superior service ensures that each antibody meets the highest standards of performance and reliability.

Featured Anti-SLC7A5 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale recombinant antibody production.

Fig.2 Gram-scale recombinant antibody production.

rAb Modalities

Creative Biolabs is dedicated to offering researchers a diverse range of high-quality recombinant antibodies in various formats. Our expertise in antibody engineering allows us to support a broad spectrum of research applications. Additionally, we provide tailored antibody engineering services to accommodate the specific needs of each project.

Fig.3 Full Length Anti-SLC7A5 Recombinant Antibody Production and Modalities.

Drug Information Targeting SLC7A5

Table 1. Therapeutic approaches targeting SLC7A5 in clinical development.

If you need further details about the SLC7A5 target, please don't hesitate to contact us by phone or email. Our experienced team is ready to help with any inquiries or issues you may encounter in your experiments, providing reliable support to help you achieve your research goals.