SPINK1

AbPlus Recombinant Antibody Products Functional Antibody Products Formats

Anti-SPINK1 Recombinant Antibody Products

Recombinant Mouse Anti-SPINK1 Antibody (CBL662) (NEUT-1978CQ)
- Species Reactivity: Human
- Type: IgG1
- Application: Neut
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For Research Use Only. Not For Clinical Use.

The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]

Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Exocrine glandular cells, Pancreatic endocrine cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (CACO-2, RT4)

Molecular function

Protease inhibitor, Serine protease inhibitor

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