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SPIRE1

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Anti-SPIRE1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Late spermatids, Early spermatids, Excitatory neurons, Inhibitory neurons, Astrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (hTERT-HME1, U-2197)

Interaction

Interacts with FMN2.

Molecular function

Actin-binding

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