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SSTR1

Anti-SSTR1 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, ELISA, IP
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- Scaffold Name: CTLA-4
- Target: Somatostatin receptor
- Species Reactivity: Hamster
- Derivation: Phage display
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, ICC
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For Research Use Only. Not For Clinical Use.
Background
Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins
Protein class
FDA approved drug targets, G-protein coupled receptors
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Hepatic stellate cells, Oligodendrocyte precursor cells, Enteroendocrine cells, Gastric mucus-secreting cells, Proximal enterocytes, Paneth cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BJ, BJ hTERT+, BJ hTERT+ SV40 Large T+, fHDF/TERT166, HeLa)
Interaction
Interacts with SKB1.
Molecular function
G-protein coupled receptor, Receptor, Transducer
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