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SSTR5
Loading...Anti-SSTR5 Products
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC-P, ICC
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- Anti-SSTR5 Immunohistochemistry Kit (VS-0525-XY6927)
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- Species Reactivity: Human
- Target: SSTR5
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
Protein class
FDA approved drug targets, G-protein coupled receptors, Plasma proteins
Predicted location
Membrane
Single cell type specificity
Not detected
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (Hep G2, PC-3)
Interaction
Heterodimer with SSTR2. Heterodimerization with SSTR2 increases cell growth inhibition activity of SSTR2.
Molecular function
G-protein coupled receptor, Receptor, Transducer
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