STK24

Recombinant Antibody Products

Anti-STK24 Recombinant Antibody Products

Hi-Affi™ Recombinant Rabbit Anti-STK24 Monoclonal Antibody (DS3437AB) (MOR-3437)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: FC, IP, WB, IHC-P, ICC/IF
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For Research Use Only. Not For Clinical Use.

This gene encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants.

Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Distal enterocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Monomer (PubMed:20124694). Interacts with CTTNBP2NL (PubMed:18782753). Interacts with RIPOR1 (via C-terminus); this interaction occurs in a PDCD10-dependent and Rho-independent manner (PubMed:27807006). Interacts with PDCD10; this interaction is required for the association of STK24 with RIPOR1 (PubMed:27807006).

Molecular function

Kinase, Serine/threonine-protein kinase, Transferase

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